CAREERS

Building a team that is eager to tackle the biggest challenges

Work with us!

At Chromodynamics, we develop microscopes that deliver breakthrough discoveries in the search for a cure for cancer. Our unique technology allows for an enormous improvement in speed, efficacy, and cost with which immunotherapies are developed. We have been recognised as one of the most exciting startups in Eindhoven and are expanding our team to ramp up our product development.

We have validated that there is a great need in cancer research for our product and are ready to scale up. To get our transformational technology ready for prime time, we need an amazing team of people! If you are convinced that you are the right person to tackle this challenge, get in touch with us! We’d love to have a chat to see if you are the right person for any of the positions below.

OPENINGS

Are you convinced that you have unique skills that can help us advance towards our goals? Have you become excited by what we are trying to achieve? Please get in touch to have a chat about whether we can mean something to each other.

INTERNSHIPS

Opening for a 15- or 20 ECTS internship for university master students.

Fluorescence microscopes image biological tissue sections to which fluorescent markers have been applied at many distinct wavelengths. The markers bind to specific antigens (proteins) on the exterior of cells, and as such enable identification of different (tumor) cell types and states.

The process of transforming raw camera sensor images into the final product, a tissue micrograph that maps out the spatial distribution of a large number of identified cell types and proteins, comprises a complex series of (nonlinear) image corrections, sub-image stitching and computational (biological) context-aware transformations. An efficient and high-throughput solution is critical due to the huge amount of image data. The design of this image processing pipeline takes place at the exciting vertex of biology, optics, and computer science.

More concretely, the project may include the following:

  • Literature studies into the state of the art of fluorescence microscopy image (pre)-processing.
  • Design of a logical image processing pipeline that takes raw camera sensor images as its input and prepares, combines, and filters them towards identification of the fluorescent markers.
    Examples of pipeline steps include:

    • Linear transformations such as noise suppression, flat-field correction, background subtraction
    • Optical aberration corrections, deconvolution with the Point Spread Function.
    • Stitching of tissue sub-images into single whole-tissue micrograph.
    • Exploration of techniques employing information theory and machine learning.
  • Proof-of-concept implementation of processing pipeline. In principle, in the Python ecosystem.
  • Evaluating the pipeline using the experimental microscope installation in our lab at the HTC.

Key facts

  • Full-time, flexible start and end dates.
  • Office and lab spaces at the High Tech Campus (HTC) in Eindhoven.
  • You will work with a small but highly skilled and motivated team.
  • Possibility to expand the internship into a graduation project.
  • Job opportunities in case of mutually positive cooperation.

If you are excited, or would like to know more, do not hesitate to contact us!

Whether it is software engineering to design fast and robust image processing algorithms, exploring new applications of our technology, performing market studies to prove their commercial potential, engineering electronics that can handle vast amounts of data, or designing the optics necessary for even more innovative solutions than what we have revealed so far, we have numerous projects lying around. Let us know what excites you and let’s make it happen!

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